What is PGT?

Preimplantation Genetic Testing (PGT) is the most advanced assisted reproductive technology. It adds genetic screening to traditional IVF, allowing doctors to select embryos with normal chromosomes and no genetic diseases before transfer.

Three Types of PGT

PGT-A (Aneuploidy Screening)

Detects abnormal chromosome numbers (should be 23 pairs, 46 total). Chromosomal abnormalities are the leading cause of IVF failure and miscarriage. PGT-A can identify over 99% of aneuploid embryos.

PGT-M (Monogenic Disease Testing)

For known single-gene genetic diseases such as Thalassemia, SMA, Cystic Fibrosis, etc. It can accurately identify embryos carrying pathogenic genes.

PGT-SR (Structural Rearrangement Testing)

Detects chromosomal structural abnormalities such as balanced translocations, suitable for couples with known structural abnormalities.

Who Should Consider PGT?

• Women over 35 years old
• Recurrent miscarriage (2+ times)
• Repeated IVF implantation failure (3+ times)
• Couples carrying genetic disease genes
• Previous birth of chromosomally abnormal child

Success Rates

• Blastocyst formation rate: 65-75%
• PGT accuracy: >99%
• Clinical pregnancy rate after normal embryo transfer: >65%
• Cumulative success rate (2-3 transfers): >90%

FAQ

Does PGT harm the embryo?

No. Modern PGT only takes a few cells from the trophectoderm (which becomes the placenta), not affecting the inner cell mass that becomes the fetus.

Can PGT guarantee a 100% healthy baby?

PGT significantly reduces genetic disease and miscarriage risks, but no technology can eliminate all possible health risks. Regular prenatal checkups are still recommended.